Morphometric Analysis of Peripapillary Thickness in Hypertensives and Normotensives using Optical Coherence Tomography (OCT)
Published: July 1, 2016 | DOI: https://doi.org/10.7860/JCDR/2016/.8105
Krishna Rao Addoor, Sulatha V. Bhandary, Lavanya G. Rao, Smita Kapoor
1. Professor and Head, Department of Ophthalmology, Kasturba Medical College, Manipal, Karnataka, India.
2. Additional Professor, Department of Ophthalmology, Kasturba Medical College, Manipal, Karnataka, India.
3. Professor and Head, Department of Ophthalmology, Srinivasa Medical College, Suratkal, Karnataka, India.
4. Junior Resident, Department of Ophthalmology, Kasturba Medical College, Manipal, Karnataka, India.
Correspondence
Dr. Sulatha V. Bhandary,
Additional Professor, Department of Ophthalmology, Kasturba Medical College, Manipal-576104, Karnataka, India.
E-mail: sulatha_bhandary@yahoo.co.in
Introduction: Hypotension following antihypertensive treatment is associated with retinal nerve fibre loss. There are studies that have reported the changes in RNFL in hypertensives.
Aim: To compare the Retinal Nerve Fibre Layer (RNFL) thickness using Optical Coherence Tomography (OCT) in hypertensive and normotensive individuals.
Materials and Methods: The cross-sectional study was conducted from October 2012 to September 2014 to compare the RNFL thickness using SD OCT in hypertensive {no other ocular or systemic co-morbidity, vision better or equal to 6/9 (n=30)} and normotensive (n=30) individuals.
Results: Statistically significant RNFL loss was detected in hypertensives (98.31 ± 7.01) when compared to the normotensives (102.51 ± 8.72) p=0.001.
Conclusion: Significant loss of RNFL in hypertensives point towards the altered autoregulation and warrants larger studies to assess the clinical relevance.
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